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Darvon

Darvon

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About Darvon

Darvon's active ingredients are propoxyphene, a narcotic (opiate) pain medication (analgesic), and acetaminophen (a non-narcotic pain medication), which relieves pain better than either medication taken alone. propoxyphene acts on the central nervous system and smooth muscle tissue, slowing the central nervous system. It is not clear exactly how acetaminophen works to ease pain.

Darvon is only available by prescription.

Darvon has few side effects when taken as recommended by your doctor, but some cautions should be observed. Interactions may occur with certain medications that could alter or increase the effect of either Darvon, or the other medication. While Darvon is a highly effective pain reliever, it has been associated with an increased risk of addiction when used improperly, or for too long. Never take Darvon in greater doses, or for a longer period of time, than recommended by your doctor.

Darvon Side Effects

Darvon side effects are usually mild, and tend to diminish over time. As with all narcotic pain medications, it can impair performance. Driving or operating heavy machinery is not advised, as Darvon can interfere with mental and physical abilities. Become familiar with your reaction to Darvon before performing potentially hazardous tasks while taking it.

Common Darvon side effects: are constipation, dizziness, dry mouth, headache, itching, nausea, sedation, sweating, vomiting, or weakness. If you feel lightheaded or nauseous, lying down may alleviate these symptoms.

Breathing: High doses of Darvon, or patient sensitivity, can cause breathing irregularity or other respiratory depression. Respiratory depression is the most serious likely side effect of Darvon, and may be more likely with certain combinations of medication. Check the drug interaction list carefully, and be cautious with any drug that slows the central nervous system or 'may cause drowsiness.' If you have breathing difficulties, Darvon may not be right for you.

Head Injuries: Propoxyphene's narcotic effects can cause an increase of pressure in the cerebral and spinal fluid. If a patient has suffered a head injury, both the pressure increase and the respiratory suppression can be exaggerated. propoxyphene may interfere with an accurate diagnosis or treatment of head injuries.

Acute Abdominal Conditions: Darvon may interfere with diagnosis and treatment of acute abdominal conditions.

Dependence: Mental and physical dependence can develop if Darvon is used for long periods of time. Long use of propoxyphene can create a tolerance condition where the medication no longer works at the initial dosage. Acetaminophen is not known to cause dependence.

Overdose: Propoxyphene overdose is characterized by slowed breathing, extreme drowsiness progressing to stupor or coma, limp muscles, or cold, clammy skin. Severe propoxyphene overdose may result in death due to cardiac arrest or stopped breathing. Acetaminophen overdose can result in severe liver poisoning, but rarely has this effect in doses under 10g. An overdose of acetaminophen may not show symptoms for two to four days, but must be treated within twenty-for hours to prevent liver damage or death. Seek emergency medical treatment immediately if you suspect an overdose.

Darvon dosage for adults is usually started at 1-2 tablets every 4 hours at a dosage of 50-100mg, and may be increased gradually if patient develops a tolerance or is in extreme pain. If you have a kidney or liver condition, or are a senior, your doctor may prescribe less frequent dosing. Severe side effects rarely occur at the prescribed dosage of Darvon.

Many cases of drug overdose involving prescription medications are related to mixing drugs that accelerate each other's effects. Never mix a powerful medication like Darvon with another prescription drug that you or your physician suspect may not be safe. Never mix Darvon with over the counter medications that have not been approved by your doctor or pharmacist, and avoid mixing it with street drugs of any type. Ignoring drug interaction warnings has resulted in fatal overdose in some patients.

Cautions: Darvon should be prescribed with caution to patients with Addison's disease or kidney, liver, thyroid, or urogenital tract problems. Tell your doctor if you have ever had an allergic reaction to Darvon, or any other medication.

Darvon Interactions

Darvon works by slowing the central nervous system. It should be used with caution with other drugs that have similar effects. Darvon can change or increase the effects of certain drugs, and your physician should be advised if you are taking any of the following.

  • Alcohol - Propoxyphene and alcohol can accelerate central nervous system depression. Avoid mixing the two, as this could result in a fatal overdose. Alcohol use combined with acetaminophen can accelerate or increase the risk of liver damage or stomach bleeding.
  • Anticonvulsant/Antiseizure medication may interact with your treatment. Be especially cautious if you use Tegretol (carbamazepine), as serious neurological disorders may result. Only your doctor can advise if this combination is safe.
  • Antihistamines like Tavist or Benadryl
  • Aspirin (or any salicylate, such as salicylamide, or salicylic acid) can cause kidney or liver damage when taken in high doses, and over long periods of time, in combination with acetaminophen. When taken in the recommended doses, for a short time, it has not been seen to produce this effect.
  • Benzodiazepines (a class of antidepressants, anti-panic agents, and muscle relaxants) such as Ativan (lorazepam), Valium (diazepam), Halcion (triazolam), Restoril (temazepam), Librium(chlordiazepoxide), Xanax (alprazolam), Tranxene-SD (clorazepate), Paxipam (halazepam), ProSom (estazolam), Klonopin (clonazepam), and others, should be used cautiously with Darvon.
  • Coumadin (warfarin) - Increased risk of bleeding.
  • Desyrel (trazodone) - Risk of additive CNS depression.
  • MAO inhibitors - Propoxyphene must not be mixed with MAO (monoamine oxidase) inhibitors such as the antidepressants Nardil, Marplan, or Parnate. It should not be used within 2 weeks of stopping these medications.
  • Narcotic pain medication of any other kind, like Codeine, Demerol (meperidine), Buprenex (buprenorphine), Darvon (propoxyphene hcl), Dilaudid (hydromorphone), MS Contin or Kadian (morphine), nalbuphine, OxyContin (propoxyphene), Stadol (butorphanol), Talwin compound (pentazocine), Vicodin (hydrocodone, acetaminophen), or Vicoprofen (hydrocodone, ibuprofen) should not be mixed with Darvon.
  • Norflex (orphenadrine) - Risk of oversedation.
  • Oral contraceptives - These may interact with acetaminophen
  • Sedatives like Fioricet (butalbital, acetaminophen, and caffeine), Fiorinal, Phenobarbitol, Seconal, or other barbiturates.
  • Sleep medication like Ambien (zolpidem), Sonata (zaleplon), or over the counter sleeping pills should be used with propoxyphene only as, and if, advised by your doctor.
  • Skeletal muscle relaxants - such as Flexeril (cyclobenzaprine), Skelaxin (metaxalone), Soma (carisoprodol), or Robaxin (methocarbamol) may increase respiratory depression when mixed with propoxyphene.
  • Street drugs of any type must never be mixed with Darvon as this could result in a fatal overdose.
  • Tranquilizers such as Haldol (haloperidol), Mellaril (thioridazine), or Thorazine (chlorpromazine) may cause oversedation.
  • Trexan (naltrexone) - Causes narcotic pain medication to be ineffective.
  • Tricyclic antidepressants such as Elavil (amitriptyline), Asendin (amoxapine), Anafranil (clomipramine), Pertofrane or Norpramin (desipramine), Sinequan (doxepin), Tofranil (imipramine), Aventyl or Pamelor (nortriptyline), Vivactil (protriptyline), and Surmontil (trimipramine), may increase the central nervous system suppressant effects from either the antidepressant, or the propoxyphene.
  • Ultram (tramadol)
  • Zidovudine (AZT, Retrovir) - Narcotic pain medication increases blood levels of this drug, potentially making side effects more severe.
  • In addition to the above medications, tell your doctor if you are using any other major antidepressants or central nervous system depressants in combination with Darvon. Be cautious about taking Darvon with any medicine warning that it 'may cause drowsiness.'
Do not mix this propoxyphene-acetaminophen combination with over the counter pain medication; acetaminophen can cause liver damage when mixed with certain pain medications. Check any cold or flu medication you may need to take to be sure it does not contain additional pain medication.

Darvon Dosages

Darvon dosage for adults is usually started at one one or two tablets every four hours, as needed. The tablets are capsule shaped, dark orange, with "Darvon-N" printed in black. Either "50" or "100" will be printed below, depending on the capsule's dosage of propoxyphene napsylate.

Darvon is manufactured in the following dosages (propoxyphene / acetaminophen):

  • Darvocet-N 50 mg/ 325 mg tablets
  • Darvocet-N 100 mg/ 650 mg tablets
Darvon Directions

If you miss a dose of Darvon, take it as soon as you remember. If you are more than halfway through your dose interval, skip the missed dose and go back to your schedule. Taking double doses of Darvon is not recommended, as it may lead to an overdose or dependence.

Do not crush tablets before taking, as this could release the drug into the bloodstream too fast, possibly resulting in an overdose.

Darvon and Pregnancy

Darvon has not been well studied for effects during pregnancy. Caution is advised in prescribing Darvon to pregnant women.

Babies born to mothers taking opiates like propoxyphene can experience withdrawal symptoms after birth. The propoxyphene withdrawal symptoms in the baby may include: irritability, hyperactivity, tremors, faster breathing, increased stools, fever, vomiting, sneezing, and yawning. The severity of the symptoms is not always tied to how much, or how long the mother used propoxyphene (or other opiate).

Darvon and Children

Darvon has not been well studied for effects on children.

Darvon and Seniors

Darvon does not seem to affect the senior population differently, but your doctor may recommend dosages that are farther apart.

There is a higher occurrence among the elderly of Addison's disease or kidney, liver, thyroid, or urogenital tract problems. Darvon should be prescribed with care to these patients, and the elderly may have to be watched more carefully for respiratory depression. Darvon should be used cautiously with any patient in a weakened condition.


Below an example of prices from a US licensed pharmacy that is currently processing orders for US board licensed physicians listed in our members area. Your meds will be shipped directly to your home:

MEDICATION
120 Tablets
Darvon 65mg (Propoxy HCL)
$93.40

Prices were verified and are subject to change
without notice. In case of any changes we will post to our website asap.
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*Shipping cost and cost of phone consultations are not included. Because discounts have been offered to subscribers you can receive a phone consultation starting at $40. This is the same type of consultation that normally costs $110-$130. When approved you will receive a legit prescription for 1 initial fill with 2 or 3 refills. Our membership fee starts at $24.95 and can save you lots of money and time!

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Darvon is a registered trademark owned by its respective owner, not by FindRxOnline.com. We do not recommend the use or import of this medication. Any pharmacies found in our member's area and forum that ship this medication are listed for discussion regarding price and availability only. You should abide by the laws in your jurisdiction even if the pharmacy notes it's OK to order. We do not provide legal or medical advice and do not condone any illegal activity.


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